Randomized Placebo-Controlled Trial to Determine the Biological Signature of Cannabidiol as a Treatment for Social Anxiety Disorder

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Social Anxiety Disorder
  • Age: Between 18 Year(s) - 45 Year(s)
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1. Right-handed.
    2. Willingness and ability to participate in the informed consent process and comply with the requirements of the study protocol.

You may not be eligible for this study if the following are true:

    1. A lifetime history of bipolar disorder, schizophrenia, psychosis, or delusional disorders.
    2. Obsessive-compulsive disorder or an eating disorder in the past 12 months.
    3. Neurocognitive disorders, intellectual disabilities, communication disorders or other cognitive dysfunction that could interfere with capacity to engage in therapy or complete study procedures.
    4. Major depressive disorder, substance or alcohol use disorder (other than nicotine) in the last 6 months.
    5. Positive urine toxicology for illicit drugs and/or cannabinoids, or self-reported use of CBD, THC or marijuana in the past 4 weeks prior to baseline.
    6. Patients with significant suicidal ideation or who have enacted suicidal behaviors within 6 months prior to intake.
    7. Patients must be free of concurrent psychotropic medication.
    8. Any concurrent psychotherapy initiated within 3 months of baseline, or ongoing psychotherapy of any duration directed specifically toward treatment of SAD.
    9. Patients with a history of head trauma causing loss of consciousness, seizure or ongoing cognitive impairment.
    10. Contraindications for MRI.



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