Ultrasound Modulation of the Globus Pallidus in Schizophrenia

Brief description of study

The Schizophrenia Research Group at NYU Langone Health, under the direction of Dr. Donald Goff, is seeking participants ages 18 – 50 with schizophrenia or schizoaffective disorder who experience continuous psychotic symptoms (delusions or hallucinations). This study evaluates whether an investigational procedure called focused ultrasound neuromodulation is effective and well-tolerated in treating schizophrenia. Focused ultrasound involves putting a device on the scalp that transmits sound waves through the skull and into the brain. We are using ultrasound to stimulate part of the brain to see if it improves symptoms of schizophrenia and whether it causes any side effects.


Clinical Study Identifier: s22-00997
ClinicalTrials.gov Identifier: NCT05643196
Principal Investigator: Donald C Goff.


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