Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression R33

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Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression R33

Brief description of study

~60 subjects with MDD will undergo MRI scanning during t-PBM (administered with an irradiance of 291.7 mW/cm2 for 333s) before and after a randomized, double-blinded, controlled 16-session course of treatment with t-PBM or sham. t-PBM will be administered via NeuroThera’s LightForce® EXPi Deep Tissue Laser TherapyTM System, Transcranial PhotoBioModulation-1000 (tPBM-2.0).

Clinical Study Identifier: s22-01065

ClinicalTrials.gov Identifier: NCT05573074

Principal Investigator: Dan Iosifescu.

Other Investigator: Thaddeus Tarpey.

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