Clinical Research Studies

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

• Conditions:
  Intradialytic Myocardial Stunning And Hemodialysis
• Age: Between 21 Year(s) - 100 Year(s)
• Gender: Male or Female

• Other Inclusion Criteria:
  

  In order to be eligible to participate in this study, an individual must meet all of the following criteria:
  1. Receiving outpatient maintenance HD therapy
  2. Age = 21 years
  3. Dialysis duration =1 year at the time of enrollment

  Enrollment in Substudies C & D additionally requires the following additional critiera:
  1. Completion of baseline echocardiography with quality sufficient to assess for the presence of IDMS
  2. For women of child-bearing capacity, a negative serum pregnancy test will be required within 48 hours.

  
  

You may not be eligible for this study if the following are true:

• An individual who meets any of the following criteria will be excluded from participation in this study:
  1. Known severe cardiomyopathy defined by history of diffuse hypokinesis/akinesis (poor function of the heart) or ejection fraction =30%
  2. Incarcerated
  3. Unable to consent

  For Substudies C and D, the following exclusion criteria apply:
  1. Chronic persistent atrial fibrillation

  For Substudy D, the following additional exclusion criteria are applied to eliminate use of medications that may interfere with myocardial catecholamine uptake:
  1. Current use of cocaine
  2. Current use of tricyclic anti-depressants