Clinical Research Studies

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

• Conditions:
  Exercise
• Age: Between 18 Year(s) - 50 Year(s)
• Gender: Male or Female

• Other Inclusion Criteria:
  

  1. Willingness to provide informed consent and participate in PRESPIRE.
  2. Able to read and speak English adequately to provide informed consent and understand verbal and written instructions.
  3. BMI < 30kg/m2.
  4. Untrained: self-reporting no more than 1 day per week of regular exercise (inclusive of walking >5,000 steps daily and commuting via bicycle).
  5. Trained: self-reporting at least 4 hours of aerobic exercise/moderate or greater intensity physical activity weekly for the past year.

  
  

You may not be eligible for this study if the following are true:

• 1. Anti-platelet medication use.
  2. Chronic inflammatory or connective tissue disease.
  3. History of bleeding or clotting disorder.
  4. Immunological deficiency.
  5. Diabetes mellitus.
  6. Stage 2 or greater hypertension on screening.
  7. Cardiovascular disease.
  8. Chronic obstructive lung disease.
  9. Active smoking.
  10. >5% body weight change over the past 6 months or plan to gain/lose weight during the study.
  11. Platelet count <100,000.
  12. Use of omega-3 fatty acid supplementation within 3 weeks of study participation.
  13. Use of drugs or supplements known to inhibit COX-1/COX-2/lipoxygenases.
  14. Corticosteroid use.
  15. Use of beta-blocker medications.
  16. Use of alpha-blocker medications.
  17. Use of NSAIDs or aspirin within 2 weeks of study participation.
  18. Vaccination within 2 weeks of study participation.
  19. Pregnancy.