Randomized Double-Blind Placebo-Controlled Study to Evaluate the Effects of EP547 in Subjects with Cholestatic Pruritus Due to Primary Biliary Cholangitis or Primary Sclerosing Cholangitis

Brief description of study

Intense. Unrelenting. Distressing. Itching.

If you have itch due to liver disease, consider participating in pruritus research. The PACIFIC study is testing an investigational drug (EP547) to see if it can help reduce itch (pruritus) in adults with Primary Biliary Cholangitis (PBC) or Primary Sclerosing Cholangitis (PSC). By participating in this study, you may be helping to advance development of a potential new treatment. Every day, research uncovers new information about medical conditions and their potential treatments. Volunteer involvement in clinical studies from participants like you, especially in rare diseases, is critical to advance development of future therapies. Results collected from clinical studies have led to thousands of medications becoming available to patients all over the world.


Clinical Study Identifier: s22-01457
Principal Investigator: Ira M. Jacobson.
Other Investigator: Mary Christine Olson.


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