A Phase 3 Multi-center Randomized Withdrawal and Long-Term Extension Study of Ampreloxetine for the Treatment of Symptomatic Neurogenic Orthostatic Hypotension in Participants with Multiple System Atrophy

Brief description of study

The purpose of this research is to study whether an investigational drug, called ampreloxetine, works and how safe it is when taken over several months to treat symptomatic neurogenic orthostatic hypotension (nOH) in people with multiple system atrophy (MSA). It will also look at the effects of ampreloxetine on general well-being and if it can improve symptoms of nOH.


Clinical Study Identifier: s23-00335


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