Clinical Research Studies

Treatments for opioid addiction exist, but effectiveness is compromised when subjects use illicit opiates during treatment. Reuse rates during treatment can be high, and reducing illicit opiate use during treatment has thus recently become a major NIDA policy goal. Our 5-minute battery indicates the numerical probability that a patient will reuse illicit opiates within the next 7-10 days. Our primary goal in this mid-scale clinical trial is to test the hypothesis that clinicians who use the output of our mobile system to adjust buprenorphine and methadone dosing achieve lower opiate reuse rates than physicians who provide care-as-usual. Our secondary goal is to examine the usability and desirability of this solution for clinicians with an eye to usability and large-scale deployment. Our third and final goal is to measure the cost-effectiveness of this solution from multiple perspectives. If we are successful it will be possible to employ an algorithmic and measurement-based approach to OUD treatment with methadone and buprenorphine which reduces reuse rates and relapse rates amongst OUD patients.