Young Onset Parkinson s disease Subtypes and Pathogenic Mechanisms
Are you eligible to participate in this study?
You may be eligible for this study if you meet the following criteria:
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Conditions: Parkinson's Disease
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Age: Between 18 Year(s) - 100 Year(s)
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Gender: Male or Female
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Other Inclusion Criteria:
- YOPD Cohort
- Male or female 18 years or older (inclusive) of any race and ethnicity.
- Diagnosis of PD confirmed by a movement disorder specialist and with an age of onset of less than or equal to the age of 50 years old.
- Willingness to undergo a skin punch biopsy.
- Late-Onset PD (LOPD) Cohort
- Male or female 18 years or older (inclusive) of any race and ethnicity.
- Diagnosis of PD confirmed by a movement disorder specialist and with an age of onset after the age of 50 years.
- Healthy Control Cohort
- Male or female 18 years or older (inclusive) of any race and ethnicity.
- Never been diagnosed with PD.
You may not be eligible for this study if the following are true:
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- Individuals with a diagnosis of atypical parkinsonism (i.e. progressive supranuclear palsy, corticobasal degeneration, multiple system atrophy) or secondary parkinsonism (i.e. normal pressure hydrocephalus, drug-induced parkinsonism).
- Individuals with a clinical history of autoimmune or chronic inflammatory disorder or exposure to chronic immunosuppressant or immunomodulatory medications.
- Individuals with a relevant dermatological condition that would prevent performing skin punch biopsies (for YOPD cohort only).
- Individuals who are pregnant.
If you are registered as a volunteer, please log in to contact the study team/express interest in this study.