Young Onset Parkinson's disease Subtypes and Pathogenic Mechanisms (YOPD Study)

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Parkinson's Disease
  • Age: Between 18 Year(s) - 100 Year(s)
  • Gender: Male or Female
  • Other Inclusion Criteria:
      YOPD Cohort
    1. Male or female 18 years or older (inclusive) of any race and ethnicity.
    2. Diagnosis of PD confirmed by a movement disorder specialist and with an age of onset of less than or equal to the age of 50 years old.
    3. Willingness to undergo a skin punch biopsy.
      Late-Onset PD (LOPD) Cohort
    1. Male or female 18 years or older (inclusive) of any race and ethnicity.
    2. Diagnosis of PD confirmed by a movement disorder specialist and with an age of onset after the age of 50 years.
      Healthy Control Cohort
    1. Male or female 18 years or older (inclusive) of any race and ethnicity.
    2. Never been diagnosed with PD.

You may not be eligible for this study if the following are true:

    1. Individuals with a diagnosis of atypical parkinsonism (i.e. progressive supranuclear palsy, corticobasal degeneration, multiple system atrophy) or secondary parkinsonism (i.e. normal pressure hydrocephalus, drug-induced parkinsonism).
    2. Individuals with a clinical history of autoimmune or chronic inflammatory disorder or exposure to chronic immunosuppressant or immunomodulatory medications.
    3. Individuals with a relevant dermatological condition that would prevent performing skin punch biopsies (for YOPD cohort only).
    4. Individuals who are pregnant.



If you are registered as a volunteer, please log in to contact the study team/express interest in this study.

Contact the research team to learn more about this study.

By clicking "Contact Research Team", your contact information will be sent securely to the research staff associated with the study. You will also receive a copy of this email in your inbox, as well as other notifications to determine your participation status in the study.