QUANTIFICATION OF MULTI-COMPARTMENT T1 RELAXATION AND MAGNETIZATION TRANSFER IN BIOLOGICAL TISSUE: FROM BIOPHYSICS TO BIOMARKERS FOR MULTIPLE SCLEROSIS

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QUANTIFICATION OF MULTI-COMPARTMENT T1 RELAXATION AND MAGNETIZATION TRANSFER IN BIOLOGICAL TISSUE: FROM BIOPHYSICS TO BIOMARKERS FOR MULTIPLE SCLEROSIS

Brief description of study

To evaluate the efficacy of multi-compartment T1 relaxation and magnetization transfer for detecting subtle changes in normal-appearing brain tissue in multiple sclerosis to detect disease progression. The primary endpoint of this study is the identification of the utility of hybrid-state qMT imaging for the assessment of MS disease progression.

Clinical Study Identifier: s23-00884

Principal Investigator: Jakob Asslaender.

Other Investigator: Timothy Michael Shepherd.

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