Site for A RANDOMIZED DOUBLE-BLIND MULTI-CENTER COMPARATIVE EFFECTIVENESS STUDY OF SPIRONOLACTONE VERSUS DOXYCYCLINE HYCLATE FOR THE TREATMENT OF ACNE IN WOMEN

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Acne
  • Age: Between 16 Year(s) - 40 Year(s)
  • Gender: Female
  • Other Inclusion Criteria:
    1. Assigned female at birth; age 16-40 years old.
    2. Has acne.
    3. Not currently pregnant or planning to become pregnant.
    4. Willing to attest to abstinence or some form of contraception for the duration of the study (4 months).

You may not be eligible for this study if the following are true:

    1. Pregnancy.
    2. Change to long-term hormonal contraception (e.g. Mirena, Nexplanon), a combined hormonal contraceptive, or other hormonal treatment in the past 3 months.
    3. History of:
      • Heart disease;
      • Renal disease;
      • Liver disease;
      • Orthostatic hypotension;
      • Addison's disease;
      • Cushing's syndrome;
      • Hyperkalemia.
    4. Allergy to tetracycline-class antibiotic.
    5. Allergy to spironolactone.
    6. Treatment with spironolactone, an oral antibiotic, laser, photodynamic therapy, or chemical peel within the past 4 weeks.
    7. Treatment with isotretinoin within the past 3 months.
    8. Treatment with a drospirenone containing combined oral contraceptive.
    9. Sebacia laser treatment within the past 12 months.



If you are registered as a volunteer, please log in to contact the study team/express interest in this study.