A Phase 1b/2 Study to Demonstrate the Safety and Efficacy of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an Ileal Pouch-Anal Anastomosis

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Ileal Pouch-anal Anastomosis (ipaa)
  • Age: Between 18 Year(s) - 99 Year(s)
  • Gender: Male or Female
  • Other Inclusion Criteria:
      Phase 1b Only
    1. Subject is a male or female and is between the age of 18 to 65 years, inclusive, at screening.
    2. Subject has had a documented pouchoscopy within 12 months prior to screening.
      Phase 2 Double-Blinded

You may not be eligible for this study if the following are true:

    1. Phase 1b Only
    2. Subject has Crohn's-like disease of the pouch, as indicated by their most recent pouchoscopy during the 12 months prior to screening.
    3. Subject has a stricture of the IPAA or afferent limb stricture, as indicated by the

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