A Phase 1b/2 Study to Demonstrate the Safety and Efficacy of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an Ileal Pouch-Anal Anastomosis

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Ileal Pouch-anal Anastomosis (ipaa)
  • Age: Between 18 Year(s) - 99 Year(s)
  • Gender: Male or Female
  • Other Inclusion Criteria:
      Phase 1b Only
    1. Subject is a male or female and is between the age of 18 to 65 years, inclusive, at screening.
    2. Subject has had a documented pouchoscopy within 12 months prior to screening.
      Phase 2 Double-Blinded

You may not be eligible for this study if the following are true:

    1. Phase 1b Only
    2. Subject has Crohn's-like disease of the pouch, as indicated by their most recent pouchoscopy during the 12 months prior to screening.
    3. Subject has a stricture of the IPAA or afferent limb stricture, as indicated by the


If you are registered as a volunteer, please log in to contact the study team/express interest in this study.

Contact the research team to learn more about this study.

By clicking "Contact Research Team", your contact information will be sent securely to the research staff associated with the study. You will also receive a copy of this email in your inbox, as well as other notifications to determine your participation status in the study.