Microbial and Host Biomarkers for Endotyping Venous Thromboembolism Patients

Brief description of study

This research aims to understand the differences between blood clotting caused by viruses affecting the whole body versus those affecting the lungs, and how different treatments affect our genes and molecules. We also want to study why some people are more likely to develop dangerous blood clots after getting treatment for vein blood clots. This study hopes to find out how treatments can be improved for people with vein blood clots.

We'll enroll patients diagnosed with vein blood clots like those in the lungs or legs, who need treatment procedures. We'll also include patients diagnosed with vein blood clots who don't need a procedure, for comparison. All patients who agree will give blood samples and other samples during the study. Those having procedures will give samples during their treatment, and some may also give samples later for follow-up research.


Clinical Study Identifier: s24-00118
Principal Investigator: Shari Barnett Brosnahan.
Other Investigators: Ezra E Dweck, Carlos Leon Alviar, Bedros Taslakian, Dustin Lynn Slagle, Clea Rose Barnett, Radu Postelnicu, Eric E Bondarsky, Jeremy Grossman, Allison Ashley Greco, Lindsay Elbaum, Benjamin Kwok, Sripal Bangalore, Leopoldo N. Segal, Nancy E Amoroso.


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