Lupus Omics Cutaneous Kidney Investigative Team: Kidney Project 1

Brief description of study

The purpose of this study is to learn more about patients with lupus (“systemic lupus erythematosus” or “SLE”) who may have injury to their kidney, which is called lupus nephritis. The goal of this study is to understand how lupus starts in the kidneys and injures the kidneys early in the course of lupus nephritis.

For this study, we will examine the kidney tissue of patients with lupus who have never had kidney involvement but now show early signs of kidney injury. The diagnosis of early kidney injury will be made through a kidney biopsy, as is done for all lupus patients suspected of having kidney involvement. To better understand early kidney injury, an extra sample of tissue will be obtained for research studies while you are having a kidney biopsy for clinical purposes.


Clinical Study Identifier: s22-01559
Principal Investigator: Jill P Buyon.


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