ALXN2220-ATTRCM-301: A Phase 3 Randomized Double-blind Placebo-controlled Multicenter Study to Evaluate the Efficacy and Safety of Amyloid Depleter ALXN2220 in Adult Participants with Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

Brief description of study

We are doing this study to learn more about an experimental drug called ALXN2220 for the proposed treatment of adult patients with ATTR-CM, and to better understand the studied disease and associated health problems.

Experimental means ALXN2220 has not been fully tested in patients with ATTR-CM yet, and it is not approved by any health authority, except for use in research studies like this one.

Clinical Study Identifier: s23-01377

ClinicalTrials.gov Identifier: NCT06183931

Principal Investigator: Jose A Alvarez-Cardona.

Other Investigators: Alex Reyentovich, Maria Alejandra Gonzalez-Duarte Briseno, Maureen Coletta Geary, Jadranka Stojanovska.

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