Clinical Research Studies

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

• Conditions:
  Gout
• Age: Between 18 Year(s) - 90 Year(s)
• Gender: Male or Female

• Other Inclusion Criteria:
  

  1. Be diagnosed with gout.
  2. Have experienced at least one gout flare attributed in the previous 12 months.
  3. Be able to swallow pills.
  4. Agree to practice effective measures of birth control if of reproductive potential.

  
  

You may not be eligible for this study if the following are true:

• 1. Diagnosis of chronic kidney disease (CKD) Stage 3B or worse
  2. Two or more episodes of renal colic in the past 5 years
  3. Unable to provide informed consent
  4. Pregnancy, planning pregnancy, or breastfeeding.
  5. Patients who have been treated with thiopurines (mercaptopurine (PURINETHOL®), azathioprine (IMURAN®), or thioguanine) in the past 12 months or currently being treated with thiopurines are not eligible for the study. Usage of the thiopurines (azathioprine and mercaptopurine) with allopurinol has been shown to cause a significant drug-drug interaction.
  6. Unlikely to survive 2 years because of comorbidities.
  7. Currently taking > 200 mg of allopurinol per day or any dose of febuxostat. Patients taking 200 mg or less of allopurinol daily may participate, provided they meet the eligibility criteria for flares and current SU, and they have not had a dose escalation in their allopurinol in the previous 6 months.
  8. Patients with known allergic or hypersensitive reactions to allopurinol and not willing to initiate febuxostat if urate lowering is indicated