Multicenter Adaptive Randomized Controlled Trial Platform To Evaluate Safety and Efficacy of Strategies and Treatments for Hospitalized Patients with Respiratory Infections(STRIVE)

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Multicenter Adaptive Randomized Controlled Trial Platform To Evaluate Safety and Efficacy of Strategies and Treatments for Hospitalized Patients with Respiratory Infections(STRIVE)

Brief description of study

We are studying an investigational drug for treatment of people in the hospital with COVID-19. This drug is investigational because it can only be used for research in hospitalized participants. This study drug is approved in Japan to treat COVID-19 only for outpatients (those not hospitalized). It is not approved by the U.S. Food and Drug Administration (FDA) or any other national government agency.

We are trying to find out if this investigational drug is effective when given in addition to the current standard treatment for COVID-19. We are also trying to make sure it is safe for people who are sick in the hospital to take.

Clinical Study Identifier: s23-00152

ClinicalTrials.gov Identifier: NCT05605093

Principal Investigator: Sam Parnia.

Other Investigators: Tanzib Hossain, Peter Spiegler, Shalinee Chawla, Britta Kumley, Hon Hei Chau, Joseph Offenbacher.

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