DISCOVERY of Risk Factors for Type 2 Diabetes in Youth Study
Are you eligible to participate in this study?
You may be eligible for this study if you meet the following criteria:
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Conditions: ObesityType 2 Diabetes
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Age: Between 9 Year(s) - 14 Year(s)
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Gender: Male or Female
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Other Inclusion Criteria:
- Children in the early and middle stages of puberty (age 9-13 years for girls, 10-14 years for boys).
- Overweight or obesity.
- Family history of T2D in 1st or 2nd degree relative.
- Personal exposure to maternal diabetes (i.e., gestational diabetes mellitus (GDM) or mother with type 1 or type 2 diabetes while pregnant with participant).
- Personal history of intrauterine growth restriction (IUGR), small for gestational age (SGA), or low birth weight.
You may not be eligible for this study if the following are true:
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- Diabetes.
- Conditions predisposing to diabetes or altering the trajectory of puberty (transplant, cancer, Down Syndrome, Turner Syndrome, Klinefelter Syndrome, ovarian/testicular failure, etc.)
- Prior treatment with insulin.
- Use of glucagon-like peptide-1 (GLP-1) receptor agonist or any weight loss medications in the 6 weeks prior to enrollment, or planning treatment with glucagon-like peptide-1 (GLP-1) receptor agonist or any weight loss medications.
- Use of metformin or any glucose lowering medication for a reason other than treatment of diabetes (e.g., for PCOS) in the 6 weeks prior to enrollment.
- History of bariatric surgery or currently planning bariatric surgery.
- Current pregnancy or currently planning pregnancy.
- Individuals who do not speak English or Spanish.
If you are registered as a volunteer, please log in to contact the study team/express interest in this study.