Effects of Elevated Intraocular Pressure on Lamina Cribrosa
Are you eligible to participate in this study?
You may be eligible for this study if you meet the following criteria:
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Conditions: Glaucoma
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Age: Between 18 years - 90 years
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Gender: Male or Female
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Other Inclusion Criteria:
Healthy volunteers- No family history (first degree relative) of glaucoma
- No history of IOP >22 mmHg
- Normal appearing optic discs and RNFL on dilated fundus examination
- Normal Swedish interactive thresholding algorithm (SITA) standard perimetry tests as defined by glaucoma hemifield test (GHT) within normal limits.
- Normal visual field as defined above.
- Either IOP between 25 to 30 mmHg with central corneal thickness < 550 micrometer, or a difference of at least 0.2 in cup to disc ratio between eyes.
- IOP or cup to disc ratio as defined for glaucoma suspects
- Two consecutive abnormal SITA standard perimetry tests with GHT outside normal limits.
You may not be eligible for this study if the following are true:
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- Media opacity (e.g. lens, vitreous, cornea) that prevents acquisition of good quality scans.
- Strabismus, nystagmus or a condition that would prevent acquisition of good quality scans.
- Diabetes with evidence of retinopathy.
- Previous intraocular surgery or ocular trauma (with the exception of laser procedures and subjects that have undergone uneventful cataract surgery more than 6 months from enrollment date).
- Neurological and non-glaucomatous causes for visual field damage.
- Any intraocular non-glaucomatous ocular disorders.
If you are registered as a volunteer, please log in to contact the study team/express interest in this study.