Neurological Emergencies Outcomes at NYU
Brief description of study
The purpose of this submission is to establish risk factors for infection after acute neurologic injury and to determine their impact on long-term outcomes. The research objectives of the proposed retrospective observational study and prospective cohort study are to: 1. Identify pre-injury and hospital course variables that affect rate of nosocomial infections. Variables to be recorded include acute pathophysiologic processes (ex. hydrocephalus, severity of hemorrhage, vasospasm, etc.), lab values, vital signs, imaging study findings, treatments/therapies, procedures, hospital complications, past medical history, social history, etc. 2. Identify impact of nosocomial infection on 3 month and 12 month outcomes in patients with acute neurologic injury. Outcomes to be measured include psychological, emotional, physical, quality of life, and global outcomes. This information may lead to the development of improved assessment of prognosis, and improved treatment strategies for patients with neurocritical illness. Additionally, data may lead to an intervention to prevent infection, such as a clinical trial of prophylactic antibiotics for patients with acute neurologic injury. Study design: This is a both a prospective cohort study and a retrospective observational cohort study.
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