Association between surrogates of arterial stiffness and urinary EDC in adolescents and young adults with Type 1 and Type 2 diabetes compared to age matched healthy adolescents

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
  • Age: Between 12 Year(s) - 23 Year(s)
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1. Adolescents 12-23 years of age with T1DM: Hba1c>8 %, duration of diabetes over 2 years, one antibody positive, undetectable insulin (<3 microIU/mL) and C-peptide (<0.8 ng/mL)
    2. Adolescents 12-23 years of age with T2DM: Hba1c>8 %, duration of diabetes over 2 years, antibody negative, detectable insulin (>3 microIU/mL) and c-peptide (<0.8 ng/mL)
    3. Healthy adolescents 12-23 year of age

You may not be eligible for this study if the following are true:

    1. Congenital heart disease, pulmonary hypertension, cardiomyopathy, thyroid disease, adrenal insufficiency
    2. Patients with thyroid disease on treatment
    3. Patients with adrenal disease
    4. Patients with hyperlipidemia with cholesterol over 250 and LDL over 130
    5. As obstructive sleep apnea: will exclude children with habitual snoring and observed apnea according to parent survey of the validated pediatric sleep questionnaire(75).
    6. Adolescents with genetic syndromes: like Turner, Down’s syndrome
    7. Females who are pregnant
    8. Significant psychiatric illness: schizophrenia, bipolar disorder, active substance abuse and uncontrolled major depression
    9. Children with developmental delay

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