Association between surrogates of arterial stiffness and urinary EDC in adolescents and young adults with Type 1 and Type 2 diabetes compared to age matched healthy adolescents.
Are you eligible to participate in this study?
You may be eligible for this study if you meet the following criteria:
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Conditions: Diabetes
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Age: Between 12 Year(s) - 23 Year(s)
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Gender: Male or Female
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Other Inclusion Criteria:
- Adolescents 12-23 years of age with T1DM: Hba1c>8 %, duration of diabetes over 2 years, one antibody positive, undetectable insulin (<3 microIU/mL) and C-peptide (<0.8 ng/mL)
- Adolescents 12-23 years of age with T2DM: Hba1c>8 %, duration of diabetes over 2 years, antibody negative, detectable insulin (>3 microIU/mL) and c-peptide (<0.8 ng/mL)
- Healthy adolescents 12-23 year of age
You may not be eligible for this study if the following are true:
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- Congenital heart disease, pulmonary hypertension, cardiomyopathy, thyroid disease, adrenal insufficiency
- Patients with thyroid disease on treatment
- Patients with adrenal disease
- Patients with hyperlipidemia with cholesterol over 250 and LDL over 130
- As obstructive sleep apnea: will exclude children with habitual snoring and observed apnea according to parent survey of the validated pediatric sleep questionnaire(75).
- Adolescents with genetic syndromes: like Turner, Down’s syndrome
- Females who are pregnant
- Significant psychiatric illness: schizophrenia, bipolar disorder, active substance abuse and uncontrolled major depression
- Children with developmental delay
If you are registered as a volunteer, please log in to contact the study team/express interest in this study.