Exhaled and nasal nitric oxide in children and adults with chronic wet cough

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Exhaled and nasal nitric oxide in children and adults with chronic wet cough

Brief description of study

Patients with chronic wet cough will undergo diagnostic evaluation to determine if there is diagnostic utility and an association between their levels of forced exhaled nitric oxide and nasal nitric oxide and ultimate diagnosis of either protracted bacterial bronchitis, cough variant asthma, primary ciliary dyskinesia or cystic fibrosis. The evaluation will be made through the combined use of nasal nitric oxide testing using a non-invasive research device (non FDA approved), forced exhaled nitric oxide testing and further standard of care diagnostic tests and procedures as clinically indicated which may include : blood test, bronchoscopy with bronchoalveolar lavage and endobronchial biopsy, sweat test, CT scans, etc.

Clinical Study Identifier: s17-00857

Principal Investigator: Mikhail Kazachkov.

Other Investigators: Robert John Giusti, Rany Condos.

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