CHRONIC VENOUS THROMBOSIS: RELIEF WITH ADJUNCTIVE CATHETER-DIRECTED THERAPY

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CHRONIC VENOUS THROMBOSIS: RELIEF WITH ADJUNCTIVE CATHETER-DIRECTED THERAPY

Brief description of study

To determine if EVT should be routinely used to treat DIO-PTS, we plan to perform a multicenter randomized clinical trial (the Chronic Venous Thrombosis: Relief with Adjunctive Catheter-Directed Therapy [C-TRACT] Trial) to establish whether EVT reduces PTS severity and improves health-related QOL with acceptable safety and costs. If so, this finding will fundamentally change DIO-PTS practice towards more frequent use of EVT. If EVT proves ineffective or unsafe, this finding will reduce or eliminate the use of potentially risky and expensive procedures. The C-TRACT Steering Committee includes accomplished DVT researchers who have specialized expertise with EVT, the conduct of multicenter DVT treatment trials (including the NHLBI-sponsored ATTRACT Trial), and the evaluation of PTS.

Clinical Study Identifier: s17-01701

ClinicalTrials.gov Identifier: NCT03250247

Principal Investigator: Vikram Rajpurohit.

Other Investigators: Glenn R Jacobowitz, Ernest S. Chiu, Frank Lewis Ross, Thomas Maldonado, Mikel Sadek.

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