Heart Attack Research Program (HARP)

Brief description of study

The Heart Attack Research Program (HARP) is a multi-discipline and mutli-center study that incorporates clinical and basic science and population health to investigate mechanisms of disease in women with Myocardial Infarction with Non-Obstructive Coronary Disease. In the main imaging study, participants will be enrolled at the time of referral for diagnostic angiography for clinically determined myocardial infarction. Participants who are fully eligible based on the angiogram will undergo three-vessel OCT at the time of diagnostic angiography and CMR within 1 week. Participants will be followed for recurrent clinical events, every 6 months, for a maximum of 10 years. Participants will have the option to have blood collection as part of the Platelet study, which will investigate platelet activity in people with MI.


Clinical Study Identifier: s16-01104
ClinicalTrials.gov Identifier: NCT02905357
Principal Investigator: Harmony R Reynolds.
Other Investigators: Alexander Slotwiner, Nathaniel Rosso Smilowitz, Jeffrey S Berger, Daniel Donohue, Rafael Harari, Lori Vales Lay, Giorgio A Medranda, Kevin P Marzo, Atul Sharma, Louai Razzouk, Cezar S Staniloae, Sripal Bangalore, Tanya M Spruill, Thomas Chengot, Ramanjit Bagga, Binita Shah, Leon Axel, Dimitrios Bliagos, Anais Hausvater, George Fernaine, Stylianos P Papadakos, Claudia C Serrano-Gomez, Anvar Babaev, Boutros Karam, Anthony T Gambino, Richard K Schwartz, Arthur Rusovici, Lindsay Elbaum, Sunil Rao, Michael J Attubato.


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