An observational study assessing the prevalence of lumbosacral spinal urate deposition in patients with tophaceous and non-tophaceous gout compared with non-gout controls using Dual-Energy CT (DECT)

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Gout
  • Age: Between 50 - 80 Years
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1. Subjects who are willing to provide informed consent
    2. Subjects between the ages of 50 to 80 years old
    3. Subjects is diagnosed with gout (for gout group)
    4. Subjects are not receiving urate lowering therapy
    5. Subjects have palpable and measurable peripheral tophi (for tophaceous gout group)

You may not be eligible for this study if the following are true:

    1. Subjects unable to provide informed consent
    2. Subjects who are not between the ages of 50 and 80 years of age.
    3. Subjects who have well-controlled gout with sUA under 6.0 mg/dL for a duration of longer than 6 months at the time of evaluation.
    4. Subjects with history of active malignancy of the spine.
    5. Subjects with known history of pseudogout, spondyloarthropathy, or any other inflammatory arthritis.
    6. Subjects who had prior treatment with pegloticase or other uricase for any reason.



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