A single center pilot study to assess the intra-observer reliability of measuring muscle strength using a hand held dynamometer in children and adults with neurofibromatosis type 1 (NF1) and type 2 (NF2)
Are you eligible to participate in this study?
You may be eligible for this study if you meet the following criteria:
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Conditions: Nf1 Or Nf2
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Age: Between 5 years - 100 years
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Gender: Male or Female
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Other Inclusion Criteria:
For Cohort 1- Subjects are at least 5 years old
- Subjects must have clinically confirmed NF1 using the NIH consensus criteria or a known NF1 mutation.
- Subjects have have <5/5 strength on MMT testing (in at least one muscle group)
- Subjects able to follow instructions and cooperate with exam to assess strength
- Subjects are at least 5 years old
- Subjects must have clinically (NIH or Manchester criteria) or genetically confirmed diagnosis of NF2
- Subjects have <5/5 strength on MMT testing (in at least one muscle group)
- Subjects able to follow instructions and cooperate with exam to assess strength
You may not be eligible for this study if the following are true:
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- Subjects with no orthopedic procedure or other major surgery that could influence extremity strength in past 6 months
- Subjects with no tibial dysplasia
If you are registered as a volunteer, please log in to contact the study team/express interest in this study.