Clinical Efficacy and Safety of Using 3.0mg Liraglutide to Treat Weight Regain After Roux-en-Y Gastric Bypass Surgery
Are you eligible to participate in this study?
You may be eligible for this study if you meet the following criteria:
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Conditions: ObesityRoux-en-y Gastric Bypass
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Age: Between 18 years - 100 years
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Gender: Male or Female
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Other Inclusion Criteria:
- =18 years who are deemed medically stable
- =18 months status-post RYGB
- BMI 27 kg/m2 or greater in the presence of at least one weight-related comorbid condition
- BMI 30 kg/m2 or greater
- Regain of =10% of maximum total body weight loss (TBWL) post-RYGB
- Ability to provide informed consent before any trial-related activities
- Express willingness to follow protocol requirements
You may not be eligible for this study if the following are true:
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- BMI of >45 kg/m2
- Pregnancy at time of enrollment
- Intention of becoming pregnant or breast feeding in the next 12 months
- Females of childbearing potential who are not using adequate contraceptive methods
- Presence of acute psychiatric problems or immaturity which would compromise cooperation with the study protocol
- Known or suspected allergy to liraglutide or any product components
- Personal or family history of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2
- History of pancreatitis
- History of Type 1 DM (Diabetes Mellitus)
- History of previous bariatric surgery other than RYGB except h/o Laparoscopic Adjustable Gastric Band (LAGB) and band removal (no current band patients)
- >10 years status-post RYGB
- < 25% TBWL at post-RYGB weight nadir
- >50% post-operative TBWL at time of screening
- Simultaneous use of any weight loss medications
- Use of insulin at the time of enrollment
- Current use of any GLP-1 agonist medication (Saxenda, Victoza, Trulicity, Ozempic, etc.)
- Histoy of taking any GLP-1 agonist medication (Saxenda, Victoza, Trulicity, Ozempic, etc.)
- Participation in another ongoing clinical study
- Conditions that, in the opinion of the principal investigator, may jeopardize the patient’s well-being and/or the soundness of this clinical study
If you are registered as a volunteer, please log in to contact the study team/express interest in this study.