Simultaneous Multinuclear Magnetic Resonance Fingerprinting for Data Fusion of Quantitative Structural and Metabolic Imaging

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    Chronic Steno-occlusive Disease, With Recurrent Transient Ischemic Attacks (tia)/minor Stroke
  • Age: Between 18 - 80 Years
  • Gender: Male or Female
  • Other Inclusion Criteria:
    Healthy subjects:
    1. Subjects who are between the ages of 18 and 80 years old
    2. Subjects who have BMI: 18 to 35 kg/m2.
    Patients:
    1. Subjects who are between the ages of 18 and 80 years old
    2. Subjects who have BMI: 18 to 35 kg/m2.
    3. Subjects with occlusion of cervical internal carotid artery, or high-grade steno-occlusive disease of the intracranial ICA and MCA
    4. Asymptomatic patients identified incidentally during routine clinical evaluation or symptomatic patients with history of transient ischemic attack or non-disabling stroke involving the ICA or MCA territory within the prior 180 days.
    5. Subjects with the ability to perform daily life activities independently
    6. Subjects with right handedness assessed via the Edinburgh Handedness Inventory.

You may not be eligible for this study if the following are true:

  • Healthy Subjects:
    1. Subjects who has the Standard contraindications to MRI.
    2. Subjects with past or present neurological disorder
    3. Subjects with alcohol or drug dependency.
    4. Subjects unable to sign informed consent or to comply with study assessments
    5. Subjects with history of planned cerebrovascular bypass surgery or intracranial stenting.
    6. Subjects with presence of potential sources of cardiogenic embolism
    Patients:
    1. Subjects who has the Standard contraindications to MRI.
    2. Subjects with past or present neurological disorder
    3. Subjects with alcohol or drug dependency.
    4. Subjects unable to sign informed consent or to comply with study assessments
    5. Subjects with history of planned cerebrovascular bypass surgery or intracranial stenting.
    6. Subjects with presence of potential sources of cardiogenic embolism



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