A pragmatic trial to evaluate the intermediate-term effects of early aggressive versus escalation therapy in people with multiple sclerosis

Brief description of study

The purpose of this research is to identify the most appropriate treatment strategy for people with multiple sclerosis (MS), especially shortly after diagnosis when it may be most possible to increase a patient's chance for preventing longer-term disability. The TREAT-MS study will help inform patients and the broader health care community on whether patients would most benefit from an earlier, aggressive therapy or if starting with a traditional therapy, followed by a switch if relapses or new MRI lesions occur, is the best approach to preventing long-term disability. An individual's perceptions of how they are doing is of utmost importance; therefore, the TREAT-MS study will capture several important and meaningful patient-reported outcomes that will shed light on what treatment strategies may be the best from a patient-centered perspective.


Clinical Study Identifier: s17-01576
ClinicalTrials.gov Identifier: NCT03500328
Principal Investigator: Lana Zhovtis Ryerson
Currently Recruiting

Contact the research team to learn more about this study.


By clicking "Contact Research Team", your contact information will be sent securely to the research staff associated with the study. You will also receive a copy of this email in your inbox, as well as other notifications to determine your participation status in the study.