In Vivo Insights of Small Vessel Changes with Age Using Ultra-Small-Superparamagnetic-Iron-Oxide (USPIO)-Enhanced MRI

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In Vivo Insights of Small Vessel Changes with Age Using Ultra-Small-Superparamagnetic-Iron-Oxide (USPIO)-Enhanced MRI

Brief description of study

This proposal seeks to perform an observational study for developing a new imaging tool using an ultra-small-superparamagnetic-iron-oxide (USPIO) contrast agent to characterize age-related microvascular changes on both 3T and 7T MRI and better understand the source and basis of brain aging.

Clinical Study Identifier: s18-00463

Principal Investigator: Yulin Ge.

Other Investigators: Elizabeth Pippa Storey, Marco Muccio, Li Jiang, Thomas M Wisniewski.

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