Prevalence and predictors of antineuronal antibody positivity in focal epilepsy

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Prevalence and predictors of antineuronal antibody positivity in focal epilepsy

Brief description of study

Antibodies are proteins that normally exist to fight off things foreign to your body (like infections), but in certain diseases, they can attack the body itself and cause disease. The purpose of this research study is to find out how often people with epilepsy carry antibodies to brain proteins and whether there are clues to whether a patient with epilepsy may have these antibodies. There are antibodies that can target proteins in the brain. This can occur in a tenth to a fifth of patients with epilepsy but the exact number is unknown. Antibodies can be detected in the blood and/or in the fluid that the brain and spinal cord are surrounded by (called the cerebrospinal fluid).

Clinical Study Identifier: s18-01053

Principal Investigator: Claude Steriade.

Other Investigators: Michael Boffa, Jacqueline A French, Orrin Devinsky.

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