Behavioral and Neural Correlates of Speech Production during Delayed Auditory Feedback in Subthalamic Nucleus: A Prospective Study in Parkinson s Subjects Undergoing Deep Brain Stimulation Surgery

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Behavioral and Neural Correlates of Speech Production during Delayed Auditory Feedback in Subthalamic Nucleus: A Prospective Study in Parkinson s Subjects Undergoing Deep Brain Stimulation Surgery

Brief description of study

The purpose of this study is to find out the role of different brain structures in the in the motor control of speech. Additionally, this study will investigate how Deep Brain Stimulation (DBS) in a part of the brain called the Subthalamic Nucleus (STN) affects the speech fluency process in people with Parkinson’s disease (PD). Parkinson patients might suffer from motor symptoms such as tremor, stiffness and stuttering. This study will provide insights into the underlying nature of stuttering, possible mechanisms of action to improve it and potentially allow for better prognostication of outcomes for patients dealing with this particular problem.

Clinical Study Identifier: s18-01124

Principal Investigator: Adeen Flinker.

Other Investigators: Alon Mogilner, Michael H. Pourfar.

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