SAMPLE (Specimen and Matched Phenotype Linked Evaluation)
Brief description of study
Researchers at NYU have developed a clinical registry containing information related to the patient’s ethnicity, race, gender, age, medications, specific disease or state of health and biorepository (tissue bank collection of blood samples, urine, and feces) of patients with autoimmune and rheumatic diseases, including but not limited to rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), psoriatic arthritis, Sjogren’s syndrome, gout, anti-phospholipid syndrome (aPLS), Beh?et’s Disease and other forms of inflammatory arthritis. To better understand the origins and factors that may make these diseases occur in the first place or progress, it is important to collect blood on healthy individuals who do not have known autoimmune or rheumatic diseases. The scientific objective is to understand what factors contribute to the risk of getting an autoimmune and/or rheumatic disease, what factors make the disease worse, what factors relate to whether a therapy helps improve disease, and what factors lead to health problems other than the specific disease. A biorepository (tissue bank) will be now be developed for the storage of genetic material (DNA), blood cell RNA, plasma, serum, feces, urine, and lymphoblastoid cell lines (LCLs) from healthy individuals.
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