Colchicine for the Treatment of Osteoarthritis of the Knee (CLOAK)

Brief description of study

Osteoarthritis (OA) is a common, painful, and debilitating form of arthritis for which no cure currently exists. The purpose of this study is to determine if colchicine is safe and effective for people with OA. Colchicine is an anti-inflammatory agent used commonly for gout. Three small studies suggest that colchicine may improve OA pain. Colchicine has not been approved by the US Food and Drug Administration (FDA) for the treatment of OA. For this reason, its use in this study is considered experimental. This study is a double-blind, randomized, placebo-controlled trial to test whether colchicine treatment of symptomatic knee OA (SKOA) patients will lower pain scores and improve physical function.

Clinical Study Identifier: s16-01796 Identifier: NCT03913442
Principal Investigator: Michael H Pillinger.

If you are registered as a volunteer, please log in to contact the study team/express interest in this study.

Contact the research team to learn more about this study.

By clicking "Contact Research Team", your contact information will be sent securely to the research staff associated with the study. You will also receive a copy of this email in your inbox, as well as other notifications to determine your participation status in the study.