Mechanisms of Vascular Aneurysms

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Mechanisms of Vascular Aneurysms

Brief description of study

Our mission is to enable the use of human tissues with outcome data by basic and clinical investigators for research into the biology, causes, prevention and therapy of patients with documented arterial pathology (e.g. aortic dissection, lower extremity aneurysm, aortic aneurysm). Paired clinical information about disease history and research into vascular events will enable clinically relevant findings. We will prospectively collect both tissue samples and blood samples to study the mechanisms of the natural history of aneurysms and potential circulating biomarkers. We will be collaborating with Dr. Gelb in order to obtain tissue and blood from healthy controls during the organ procurement. We will also collect relevant clinical and medical information on these subjects and continue to collect follow-up information on the surgical patients using their medical records in order to follow their outcome. The tissue and blood will be stored indefinitely.

Clinical Study Identifier: s16-01807

Principal Investigator: Bhama Ramkhelawon.

Other Investigators: Patrick J Lamparello, Thomas Maldonado, Katherine Teter, Bruce E Gelb, Joanelle Z. Lugo, Karan Garg, Aubrey C Galloway, Todd L. Berland, Neal S Cayne, Elias A Zias, Mikel Sadek.

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