Imaging biomarkers of knee osteoarthritis

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions:
  • Age: Between 40 - 75 Years
  • Gender: Male or Female
  • Other Inclusion Criteria:
    1. Subjects in the HJD OA database
    2. Subjects who are between the ages of 40-75 years with high risk of developing OA as defined by
      • KL score of 0
      • Knee pain present in at least 1 knee
      • Normal radiographs,
      • At least one abnormal clinical MR finding such as prior knee injury, overweight or traumatic bone marrow edema lesions
    3. Subjects with ages 40-75 with early OA as determined by KL scores 1-2
    4. Healthy controls in the HJD OA database (KL score 0, no knee pain, no meniscal or ligament tears)
    5. Healthy controls from the NYU Radiology volunteer database with no prior medical history of OA, knee pain, meniscal or ligament tears

You may not be eligible for this study if the following are true:

    1. Subjects with contraindications for MRIs
    2. Subjects with any joint disease other than knee OA, corticosteroid injections within the previous 3 months, and history of avascular necrosis, Paget’s disease of bone, Wilson’s disease, gout, total knee replacement
    3. Subjects with major co-morbidities such as diabetes, mellitus, cancer, congestive heart failure and chronic infectious diseases
    4. Subjects with alignment interventions such as insoles and knee braces

If you are registered as a volunteer, please log in to contact the study team/express interest in this study.