A Prospective Randomized Trial to Assess PO versus IV Antibiotics for the Treatment of Post-op Wound Infection after Extremity Fractures (POvIV Study)
Brief description of study
This research study is being done to help us determine the best treatment for infections like yours. Infections after surgery occur fairly often. Usually these infections are treated with antibiotics for up to six weeks. Based on information given to us from the participating hospitals, we know that most often, the standard treatment uses intravenous (IV)(liquid) medicine given through a small tube called a catheter, which is placed in your arm. But we also know that there are some differences in what is normally given at each participating hospital. So, in some places oral antibiotics (pills) are used. The standard method of delivery (how you received your antibiotics) is determined by the physicians who care for you at your hospital. There has not been a study to compare these two types of treatment for infections such as yours. Since we do not know if taking medication in pill form works as well as medication given intravenously, this study will compare the two forms of treatment. The study will also compare the costs of these two treatments.
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