MICROBiome Involvement in Outcomes of Methotrexate Efficacy-RA

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MICROBiome Involvement in Outcomes of Methotrexate Efficacy-RA

Brief description of study

This is a prospective, observational, proof-of-principle, open-label, single-blinded study looking at the effects of the gut microbiome on the metabolism and response to methotrexate treatment and related medications. MTX will be taken at standard-of-care doses in drug-naïve RA patients who have active disease and have not received other disease-modifying therapies (as defined by the inclusion/exclusion criteria).

Clinical Study Identifier: s19-00805

Principal Investigator: Jose U Scher.

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