17 "COVID-19" clinical trials found.
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A Multicenter Adaptive Randomized Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of COVID-19 in Hospitalized Adults
COVID-19 is a respiratory disease caused by a novel coronavirus (SARS-CoV-2) and causes substantial morbidity and mortality. There are no approved medicines to treat COVID-19. ...
Phase
Interventional
Match Level: Exact
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A randomized placebo-controlled safety and dose-finding study for the use of the IL-6 inhibitor clazakizumab in patients with life-threatening COVID-19 infection
The purpose of this research study is to investigate the safety of treatment with an investigational drug called clazakizumab compared to a placebo (inactive substance) ...
Phase
Interventional
Match Level: Exact
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Efficacy of Hydroxychloroquine for Post-exposure Prophylaxis (PEP) to Prevent Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Among Adults Exposed to Coronavirus Disease (COVID-19): a Blinded Randomized Study
The purpose of this study is to understand if taking a malaria, autoimmunity, and arthritis medication called hydroxychloroquine can reduce the risk of becoming infected ...
Phase
Match Level: Exact
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COVID-19 - Emergency IND
This is a prospective multicenter registry with an embedded open-label randomized clinical trial to determine the effects of standard of care treatment vs. standard of ...
Phase
Interventional
Match Level: Exact
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A Phase 1/2 Placebo-Controlled Randomized Observer-Blind Dose-Finding Study to Describe the Safety Tolerability Immunogenicity and Potential Efficacy of SARS CoV 2 RNA Vaccine Candidates Against COVID 19 in Healthy Adults
The World Health Organization (WHO) has declared COVID-19 to be a pandemic; finding a vaccine to prevent COVID-19 is an urgent need. The study will ...
Phase
Accepts Healthy Volunteers
Match Level: Exact
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Convalescent Plasma To Limit Coronavirus Associated Complications: A Randomized Blinded Phase 2 Study Comparing The Efficacy And Safety Of Anti-Sars-Cov-2 Plasma To Placebo In Covid-19 Hospitalized Patients
The purpose of the study is to find out if convalescent plasma (the liquid portion of blood of patients who recover from COVID-19) can prevent ...
Phase
Interventional
Match Level: Exact
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BARCONA Trial: A Randomized Trial of Bardoxolone Methyl in Patients Infected with SARS-Corona Virus-2 (COVID-19)
The purpose of this research study is to find out if bardoxolone methyl is safe to use for people with COVID-19 and if it will ...
Phase
Interventional
Match Level: Exact
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COVID-19 AND LACTATING MOTHERS (CALM): AN OBSERVATIONAL STUDY OF COVID-19 TRANSMISSION RISKS BETWEEN PARENT AND CHILD THROUGH HUMAN LACTATION
The purpose of this study is to determine if there may be virus causing COVID-19 in breast milk, skin swabs and blood samples we collect ...
Phase N/A Accepts Healthy Volunteers
Match Level: Exact
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Type I Interferon in COVID-19
The purpose of this research study is to look at the genes (DNA) and biomarkers in the blood of patients that test COVID-positive or are ...
Phase N/A
Observational
Accepts Healthy Volunteers
Match Level: Exact
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A Multicenter Adaptive Randomized Controlled Platform Trial of the Safety and Efficacy of Antithrombotic Strategies in Hospitalized Adults with COVID-19
Patients with COVID-19 disease are at risk of blood clots, which may affect many parts of the body. The purpose of this study is to ...
Phase
Interventional
Match Level: Exact
