15 "COVID-19" clinical trials found.
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A Multicenter Adaptive Randomized Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of COVID-19 in Hospitalized Adults
COVID-19 is a respiratory disease caused by a novel coronavirus (SARS-CoV-2) and causes substantial morbidity and mortality. There are no approved medicines to treat COVID-19. ...
Phase
Interventional
Match Level: Exact
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An Adaptive Phase 2/3 Randomized Double-Blind Placebo-Controlled Study Assessing Efficacy and Safety of Sarilumab for Hospitalized Patients with COVID-19
The main purpose of this study is to determine if sarilumab is safe and if it can decrease the amount of time someone would have ...
Phase
Interventional
Match Level: Exact
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A randomized placebo-controlled safety and dose-finding study for the use of the IL-6 inhibitor clazakizumab in patients with life-threatening COVID-19 infection
The purpose of this research study is to investigate the safety of treatment with an investigational drug called clazakizumab compared to a placebo (inactive substance) ...
Phase
Interventional
Match Level: Exact
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Emergency Hyperbaric Oxygen for Respiratory Distress or Failure for COVID-19 Patients
The purpose of this study is to investigate the use of hyperbaric oxygen therapy to treat respiratory distress in patients who have tested positive for ...
Phase N/A Interventional
Match Level: Exact
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Efficacy of Hydroxychloroquine for Post-exposure Prophylaxis (PEP) to Prevent Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Among Adults Exposed to Coronavirus Disease (COVID-19): a Blinded Randomized Study
The purpose of this study is to understand if taking a malaria, autoimmunity, and arthritis medication called hydroxychloroquine can reduce the risk of becoming infected ...
Phase
Match Level: Exact
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COVID-19 - Emergency IND
This is a prospective multicenter registry with an embedded open-label randomized clinical trial to determine the effects of standard of care treatment vs. standard of ...
Phase
Interventional
Match Level: Exact
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COLCHICINE CORONAVIRUS SARS-CoV2 TRIAL (COLCORONA)
COVID-19 is due to an infection by the beta-coronavirus SARS-CoV2. This will be a randomized, double-blind, placebo-controlled study. Following signature of the informed consent form, ...
Phase
Interventional
Match Level: Exact
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A Randomized Trial of Anticoagulation Strategies in COVID-19:PROTECT-COVID 19
Anticoagulation medicines are used to reduce the risk of blood clot formation in the blood vessels. Blood clots that form in blood vessels can travel ...
Phase
Interventional
Match Level: Exact
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A Phase 1/2 Placebo-Controlled Randomized Observer-Blind Dose-Finding Study to Describe the Safety Tolerability Immunogenicity and Potential Efficacy of SARS CoV 2 RNA Vaccine Candidates Against COVID 19 in Healthy Adults
The World Health Organization (WHO) has declared COVID-19 to be a pandemic; finding a vaccine to prevent COVID-19 is an urgent need. The study will ...
Phase
Accepts Healthy Volunteers
Match Level: Exact
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Convalescent Plasma To Limit Coronavirus Associated Complications: A Randomized Blinded Phase 2 Study Comparing The Efficacy And Safety Of Anti-Sars-Cov-2 Plasma To Placebo In Covid-19 Hospitalized Patients
The purpose of the study is to find out if convalescent plasma (the liquid portion of blood of patients who recover from COVID-19) can prevent ...
Phase
Interventional
Match Level: Exact
