11 clinical trials found.
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An Observational Study of Patients Undergoing Therapy for Chronic Hepatitis B (HBV) Infection
The TARGET-HBV study engages an observational research design to conduct a comprehensive review of therapeutic outcomes for patients with chronic hepatitis B (HBV) who are ...Phase N/A
TRIAL ROLE: Principal Investigator
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A Study to Evaluate the Degree of Steatosis in Subjects with any Feature of the Metabolic Syndrome in Primary Care or Endocrine Clinics for Non-Alcoholic Fatty Liver Disease (NAFLD) Utilizing Vibration Controlled Transient Elastography (VCTE) and Controll
The purpose of this study is to find out if any of the volunteers have Non-Alcoholic Fatty Liver Disease (NAFLD) which can be diagnosed through ...Phase N/A TRIAL ROLE: Principal Investigator
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A Seamless Adaptive Phase 2b/3 Double-Blind Randomized Placebo-controlled Multicenter International Study Evaluating the Efficacy and Safety of Belapectin (GR-MD-02) for the Prevention of Esophageal Varices in NASH Cirrhosis
The purpose of this study is to find out about the safety and efficacy (how well a drug works) of Belapectin (GR-MD-002) for the prevention ...Phase
TRIAL ROLE: Principal Investigator
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Evaluation of Efficacy Safety and Tolerability of NGM282 (Aldafermin) in a Phase 2b Randomized Double-blind Placebo-controlled Multi-center Study in Subjects with Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (ALPINE 4)
The purpose of the study is to examine the effectiveness of aldafermin for the treatment of cirrhosis caused by nonalcoholic steatohepatitis (NASH). The study will ...Phase
TRIAL ROLE: Principal Investigator
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Measurement of Thrombelastography as an alternative means to guide blood product use before invasive procedures in cirrhosis with severe coagulopathy: An observational study
The purpose of this study is to test the use of a blood test known as thromboelastography (TEG). This study will help us see if ...Phase N/A TRIAL ROLE: Sub Investigator
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A 5-year Longitudinal Observational Study of Patients with Primary Biliary Cholangitis
This study will examine subjects with biliary cholangitis (PBC) which is a chronic, or long-term, disease of the liver characterized by damaged bile ducts due ...Phase N/A TRIAL ROLE: Sub Investigator
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A Randomized Double-Blind Placebo-Controlled Phase 2 Study Comparing the Efficacy and Safety of Tirzepatide versus Placebo in Patients with Nonalcoholic Steatohepatitis (NASH)
This study will examen whether the investigational drug, tirzepatide, is safe and able to help study participants with nonalcoholic steatohepatitis (NASH). “Investigational” means that the ...Phase
TRIAL ROLE: Sub Investigator
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A Double-Blind Randomized Placebo-Controlled Study and Open-Label Long Term Extension of study drug in Patients with Primary Biliary Cholangitis with Inadequate Response or Intolerance to Ursodeoxycholic Acid
The main purpose is to study the effect of daily oral administration of 80 mg elafibranor on cholestasis (impairment of bile formation and/or bile ...Phase
TRIAL ROLE: Sub Investigator
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ASSURE: An Open Label Long-Term Study to Evaluate the Safety and Tolerability of Seladelpar in Subjects with Primary Biliary Cholangitis (PBC)
The purpose of this research study is to evaluate the long-term safety and tolerability of seladelpar in treating PBC patients. Primary Biliary cholangitis (PBC) is ...Phase
TRIAL ROLE: Sub Investigator
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RESPONSE: A Placebo-controlled Randomized Phase 3 Study to Evaluate the Efficacy and Safety of Seladelpar in Patients With Primary Biliary Cholangitis (PBC) and an Inadequate Response to or an Intolerance to Ursodeoxycholic Acid (UDCA)
The purpose of this study, which involves research, is to determine if an investigational drug, seladelpar,is safe and effective in treating patients with PBC ...Phase
TRIAL ROLE: Sub Investigator
