12 clinical trials found.
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A Phase 3 Matrix Design Partially Double-Blind Randomized Study of the Efficacy and Safety of 50 mg Lonafarnib/100 mg Ritonavir BID with and without 180 mcg PEG IFN-alfa-2a for 48 Weeks Compared with PEG IFN-alfa-2a Monotherapy and Placebo Treatment in Patients Chronically Infected with Hepatitis Delta Virus Being Maintained on Anti-HBV Nucleos(t)ide Therapy (D-LIVR)
Although there is no preventative vaccine or approved treatment for HDV, researchers are studying new treatments for HDV. This research study is designed to learn ...Phase
Interventional
TRIAL ROLE: Principal Investigator
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An Observational Study of Patients Undergoing Therapy for Chronic Hepatitis B (HBV) Infection
The TARGET-HBV study engages an observational research design to conduct a comprehensive review of therapeutic outcomes for patients with chronic hepatitis B (HBV) who are ...Phase N/A TRIAL ROLE: Principal Investigator
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A Study to Evaluate the Degree of Steatosis in Subjects with any Feature of the Metabolic Syndrome in Primary Care or Endocrine Clinics for Non-Alcoholic Fatty Liver Disease (NAFLD) Utilizing Vibration Controlled Transient Elastography (VCTE) and Controll
The purpose of this study is to find out if any of the volunteers have Non-Alcoholic Fatty Liver Disease (NAFLD) which can be diagnosed through ...Phase N/A TRIAL ROLE: Principal Investigator
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A Seamless Adaptive Phase 2b/3 Double-Blind Randomized Placebo-controlled Multicenter International Study Evaluating the Efficacy and Safety of Belapectin (GR-MD-02) for the Prevention of Esophageal Varices in NASH Cirrhosis
The purpose of this study is to find out about the safety and efficacy (how well a drug works) of Belapectin (GR-MD-002) for the prevention ...Phase
TRIAL ROLE: Principal Investigator
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Evaluation of Efficacy Safety and Tolerability of NGM282 (Aldafermin) in a Phase 2b Randomized Double-blind Placebo-controlled Multi-center Study in Subjects with Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (ALPINE 4)
The purpose of the study is to examine the effectiveness of aldafermin for the treatment of cirrhosis caused by nonalcoholic steatohepatitis (NASH). The study will ...Phase
Interventional
TRIAL ROLE: Principal Investigator
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Measurement of Thrombelastography as an alternative means to guide blood product use before invasive procedures in cirrhosis with severe coagulopathy: An observational study
The purpose of this study is to test the use of a blood test known as thromboelastography (TEG). This study will help us see if ...Phase N/A TRIAL ROLE: Sub Investigator
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A 5-year Longitudinal Observational Study of Patients with Primary Biliary Cholangitis
This study will examine subjects with biliary cholangitis (PBC) which is a chronic, or long-term, disease of the liver characterized by damaged bile ducts due ...Phase N/A TRIAL ROLE: Sub Investigator
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A Randomized Double-Blind Placebo-Controlled Phase 2 Study Comparing the Efficacy and Safety of Tirzepatide versus Placebo in Patients with Nonalcoholic Steatohepatitis (NASH)
This study will examen whether the investigational drug, tirzepatide, is safe and able to help study participants with nonalcoholic steatohepatitis (NASH). “Investigational” means that the ...Phase
Interventional
TRIAL ROLE: Sub Investigator
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A Phase 2b Randomized Double Blind Placebo-Controlled Multicenter Study Evaluating Safety and Efficacy of EDP-305 in Subjects with Liver Biopsy Proven Non- Alcoholic Steatohepatitis (NASH) (ARGON-2)
The purpose of this study is to compare the effects of the EDP-305 with placebo to see which treatment is better or is safer than ...Phase
Interventional
TRIAL ROLE: Sub Investigator
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Phase IIb Multi-Center Randomised Partial-Blind Parallel Cohort Study to Assess the Efficacy and Safety of Treatment with GSK3228836 in Participants with Chronic Hepatitis B Virus (B-Clear)
GSK3228836 (the study drug) is an experimental new drug for treating chronic hepatitis B (CHB) and is not approved by the United States Food and ...Phase
Interventional
TRIAL ROLE: Sub Investigator
