13 clinical trials found.
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A Phase 2 Randomized Double-Blind Placebo-Controlled Study of the Safety and Efficacy of BMS-986165 in Subjects with Moderate to Severe Crohn's Disease
The purpose of this research study is to measure how effective and how safe BMS-986165 is in treating study participants with moderate to severe Crohn ...Phase
Interventional
TRIAL ROLE: Principal Investigator
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A Long-Term Extension Study to Evaluate the Safety of Filgotinib in Subjects with Ulcerative Colitis
The primary objective of this study is to observe the long-term safety of filgotinib in subjects who have completed or met protocol specified efficacy discontinuation ...Phase
Interventional
TRIAL ROLE: Principal Investigator
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A Long-Term Extension Study to Evaluate the Safety of Filgotinib in Subjects with Crohn's Disease
The primary objective of this study is to observe the long-term safety of filgotinib in subjects who have completed or met protocol specified efficacy discontinuation ...Phase
Interventional
TRIAL ROLE: Principal Investigator
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Combined Phase 3 Double-blind Randomized Placebo-Controlled Studies Evaluating the Efficacy and Safety of Filgotinib in the Induction and Maintenance of Remission in Subjects with Moderately to Severely Active Crohn's Disease
The primary objectives of this study are to evaluate the safety and efficacy of filgotinib during induction and maintenance treatment of moderately to severely active ...Phase
Interventional
TRIAL ROLE: Principal Investigator
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A Phase 3 Multicenter Randomized Double-Blind Parallel Placebo-Controlled Induction Study of Mirikizumab in Conventional-Failed and Biologic-Failed Patients with Moderately to Severely Active Ulcerative Colitis
The purpose of this research is to study mirikizumab, an investigational drug, developed as a potential treatment for Ulcerative Colitis (UC). The study includes a ...Phase
Interventional
TRIAL ROLE: Principal Investigator
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A Phase 2 Randomized Double-Blind Placebo-Controlled Study of the Safety and Efficacy of BMS-986165 in Subjects with Moderate to Severe Ulcerative Colitis
The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called BMS-986165 as a possible treatment for ulcerative colitis ...Phase
Interventional
TRIAL ROLE: Principal Investigator
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A Phase II Randomized Parallel-Group Double-Blind Double-Dummy Placebo-Controlled Multicenter Study To Evaluate The Efficacy Safety And Pharmacokinetics Of UTTR1147A Compared With Placebo And Compared With Vedolizumab In Patients
The purpose of this study is to compare the effects of UTTR1147A versus placebo (An inactive substance) and versus vedolizumab (ENTYVIO) on you and your ...Phase
Interventional
TRIAL ROLE: Principal Investigator
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M14-431 A Multicenter Randomized Double-Blind Placebo-Controlled Induction Study of the Efficacy and Safety of Upadacitinib (ABT 494) in Subject's with Moderately to Severely Active Crohn's Disease who have Inadequately Responded to or are Intolerant t
The purpose of this study is to evaluate the safety of upadacitinib and determine how well it works, as well as the pharmacokinetics (PK) (how ...Phase
Interventional
TRIAL ROLE: Sub Investigator
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GA29144: A Phase III Randomized Double-Blind Placebo-Controlled Multicenter Study To Evaluate The Efficacy And Safety Of Etrolizumab As An Induction And Maintenance Treatment For Patients With Moderately To Severely Active Crohn s Disease
The purpose of this study is to determine whether etrolizumab is safe and to see how well it works in treating patients with moderately to ...Phase
Interventional
TRIAL ROLE: Sub Investigator
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ECO-RESET: A Phase 2B Randomized Double-Blind Placebo-Controlled Multiple Dose Multicenter Study to Assess Efficacy and Safety of SER-287 in Adults with Active Mild-to-Moderate Ulcerative Colitis
The purpose of this research is to study SER-287 an investigational drug, developed as a potential treatment for Ulcerative Colitis (UC). The study will look ...Phase
Interventional
TRIAL ROLE: Sub Investigator
