4 clinical trials found.
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A 2-Part Multicenter Randomized Blinded Active-Controlled Phase 2 Study to Sequentially Evaluate the Safety and Efficacy of BIIB091 Monotherapy and BIIB091 Combination Therapy With Diroximel Fumarate in Participants With Relapsing Forms of Multiple Sclerosis
The purpose of this research study is to determine how effective the study treatment BIIB091 is in treating patients with Multiple Sclerosis (MS) alone and ...Phase
TRIAL ROLE: Principal Investigator
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Phase 2/3 Multistage Multicenter Randomized Double-Blind Placebo-Controlled Parallel Group Withdrawal Study to Evaluate the Efficacy and Safety of Nipocalimab Administered to Adults with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
The purpose of this study is to see if nipocalimab is safe and useful for treating participants with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP). This is ...Phase
TRIAL ROLE: Principal Investigator
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A randomized double-blind double-dummy parallel-group study comparing the efficacy and safety of remibrutinib versus teriflunomide in participants with relapsing multiple sclerosis followed by extended treatment with open-label remibrutinib
The purpose of this research study is to compare remibrutinib and teriflunomide safety and efficacy in patients with relapsing forms of Multiple Sclerosis (RMS).Phase
TRIAL ROLE: Principal Investigator
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Master protocol of two independent randomized double-blind Phase 3 studies comparing efficacy and safety of frexalimab (SAR441344) to teriflunomide in adult participants with relapsing forms of multiple sclerosis.
This clinical trial aims to assess the effectiveness and safety of an investigational drug, frexalimab, for treating relapsing multiple sclerosis (RMS). Frexalimab works by targeting ...Phase
TRIAL ROLE: Principal Investigator
