12 clinical trials found.
-
Study of a Prospective Adult Research Cohort with Inflammatory Bowel Disease (SPARC IBD)
Inflammatory Bowel Diseases (IBD) are treated with many different medications, none of which are 100% effective. One of the challenges of treating IBD is to ...Phase N/A
TRIAL ROLE: Sub Investigator
-
A phase III randomized double blind parallel group placebo controlled international multicentre study to assess efficacy and safety of Cx601 adult allogeneic expanded adipose-derived stem cells (eASC) for the treatment of complex perianal fistula(
The purpose of this study is to confirm (1) how well the investigational drug, Cx601, works at a single dose of 120 million cells compared ...Phase
TRIAL ROLE: Sub Investigator
-
Combined Phase 3 Double-blind Randomized Placebo-Controlled Studies Evaluating the Efficacy and Safety of Filgotinib in the Induction and Maintenance of Remission in Subjects with Moderately to Severely Active Crohn s Disease
The purpose of this study is to see if filgotinib is effective and safe in treating people with moderate to severe Crohn’s disease. The ...Phase
TRIAL ROLE: Sub Investigator
-
Identify predictors that distinguish between Tofacitinib responders and non-responders based on genotype and cellular and molecular profiles from pinch biopsies blood and stool samples
The purpose of this study is to identify a set of biomarkers that will predict response to tofacitinib therapy in patients with ulcerative colitis (UC ...Phase N/A TRIAL ROLE: Sub Investigator
-
Serologic Testing and Genomic Analysis of Autoimmune ImmuneMediated and Rheumatic Patients with COVID-19 (SAGA)
The purpose of this study is to obtain blood samples and nasal swab samples of patients with autoimmune and inflammatory diseases to see if certain ...Phase N/A TRIAL ROLE: Sub Investigator
-
A Randomized Double-Blind Placebo-Controlled. Multi-center Proof-of-Mechanism Phase 2a Study to Evaluate the Safety Tolerability and efficacy of TAK-018 (EB8018) for the Prevention of Post-Operative Crohn s Disease Recurrence.
The main purpose of this study is to evaluate how safe and tolerable a drug called TAK-018 (or sibofimloc,the “Takeda Study Drug”) is in ...Phase
TRIAL ROLE: Sub Investigator
-
Monitoring and Prediction of Treatment Response in Crohn s Disease with Dual-Energy CT Enterography
The purpose of this study is to prospectively evaluate the use of dual-energy CT enterography (DECTE) obtained iodine density and iodine density maps to monitor ...Phase N/A TRIAL ROLE: Co-Investigator
-
A Randomized Controlled Trial to compare the effectiveness of Fecal Microbiota Transplantation (FMT) in combination with Bezlotoxumab compared to FMT and placebo for the prevention of CDI recurrence in patients with Inflammatory Bowel Disease and Recurrent Clostridium difficile Infection
This study will find out if fecal microbiota transplantation (also known as FMT) paired with Bezlotoxumab compared to FMT and placebo is a better treatment ...Phase
TRIAL ROLE: Sub Investigator
-
A Randomized Placebo-Controlled Double-Blind Phase 1 Study of ART24 in Subjects Recently Cured of a Clostridioides difficile Infection (CDI)
The purpose of this study is to evaluate the safety and tolerability of ART24 after 28 days of daily administration for subjects who have already ...Phase
TRIAL ROLE: Sub Investigator
-
A Multicenter Randomized Double-Blind Parallel-Group Study to Assess the Efficacy and Safety of Oral Etrasimod as Induction and Maintenance Therapy for Moderately to Severely Active Crohn s Disease
The purpose of this study is to assess an investigational drug called etrasimod (also referred to as the “study drug”) in the treatment of Crohn ...Phase
TRIAL ROLE: Sub Investigator
