10 clinical trials found.
-
Transcranial Photobiomodulation for Alzheimer's Disease (TRAP-AD)
People with mild cognitive impairment (MCI) have more memory problems than normal for people their age, but their symptoms are not as severe as those ...Phase
TRIAL ROLE: Principal Investigator
-
A Pilot Phase II Open-Label Single-Center Study of Sodium-Glucose Cotransporter-2 Inhibitor Empagliflozin in Major Depressive Disorder
The purpose of this research study is to test whether empagliflozin, a medication part of a group known as sodium-glucose cotransporter-2 inhibitors (SGLT2) inhibitors, might ...Phase
TRIAL ROLE: Principal Investigator
-
Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression (TRIADE-R33)
The purpose of this research study is to determine if application of near infrared energy to the forehead can change blood flow in the brains ...Phase
TRIAL ROLE: Principal Investigator
-
Neuroenergetic Adaptations in Alzheimer's Disease: Implications on Amyloid Burden and Cognition
The purpose of this study is to see if there is a relationship between energy production in the brain and risk for Alzheimer's disease ...Phase N/A
Accepts Healthy Volunteer
TRIAL ROLE: Sub Investigator
-
Neurobiology of Sensory Phenomena in Obsessive-Compulsive Disorder
The purpose of this study is to investigate brain functioning in patients with obsessive-compulsive disorder (OCD), their siblings, and healthy individuals who do not have ...Phase N/A Accepts Healthy Volunteer
TRIAL ROLE: Sub Investigator
-
Assessment of glutamate neurotransmission brain bioenergetics and neuroinflammation in major depressive disorder using TSPO PET and MRI
The purpose of this study is to develop PET/MRI techniques for accurate assessment of changes in signal transmission, energy levels and inflammation in the ...Phase N/A Accepts Healthy Volunteer
TRIAL ROLE: Sub Investigator
-
Depression treatment and A dynamics: A study of Alzheimer s disease risk
The purpose of this research study is to test if a reduction in depressive symptoms in response to treatment with an antidepressant improves levels of ...Phase
Accepts Healthy Volunteer
TRIAL ROLE: Sub Investigator
-
Heterogeneity in OCD and Depression
The purpose of this study is to look at brain functioning in patients with obsessive-compulsive disorder (OCD) or major depressive disorder (depression, MDD). Not all ...Phase N/A Accepts Healthy Volunteer
TRIAL ROLE: Sub Investigator
-
Assessment of immunological and vascular dysfunction in neuropsychiatric post-acute sequelae of SARS-CoV-2 (long COVID-19) using TSPO PET and MRI
The purpose of this study is to develop brain imaging (PET/MRI) techniques to accurately assess immune system and blood vessel dysfunction in the brain ...Phase N/A Accepts Healthy Volunteer
TRIAL ROLE: Sub Investigator
-
Role of the Decision-Making Reference Point in Cognition and Psychopathology
Mood disorders are characterized by a tendency to subjectively evaluate objectively positive outcomes in a negative light. A fundamental feature of nearly all standard models ...Phase N/A Accepts Healthy Volunteer
TRIAL ROLE: Sub Investigator
