5 clinical trials found.
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Mechanistic basis for impaired B cell depletion after anti-CD20 treatment of African American with neuro-inflammatory disorders
The purpose of this research is to better understand why African Americans with Multiple Sclerosis (MS), Neuromyelitis optica (NMO), or other neuroinflammatory disorders, have fast ... -
A single-center observational study of the prevalence and characteristics of clutter and hoarding disorder in an MS population
The purpose of this study is to determine the prevalence of hoarding or cluttering in individuals with Multiple Sclerosis (MS), and to determine if this ... -
A pragmatic trial to evaluate the intermediate-term effects of early aggressive versus escalation therapy in people with multiple sclerosis
The purpose of this research is to identify the most appropriate treatment strategy for people with multiple sclerosis (MS), especially shortly after diagnosis when it ... -
Mesoscopic Biomarkers of Neurodegeneration and Inflammation with Diffusion MRI
The purpose of this study is to track both neurodegeneration and inflammation in multiple sclerosis (MS) disease progression by taking pictures using Magnetic Resonance Imaging ... -
A Phase III Multicenter Randomized Double-Blind Double-Dummy Study to Evaluate Safety and Efficacy of Ocrelizumab in Children and Adolescents with Relapsing-Remitting Multiple sclerosis (Operetta 2)
The study will evaluate the safety and efficacy of ocrelizumab compared with fingolimod in children and adolescents with Relapsing-Remitting Multiple sclerosis (RRMS) The purpose of ...
