13 clinical trials found.
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Phase 1 Clinical Trial of Innate Immunity Stimulation via TLR9 in Early AD (Part the Cloud)
The purpose of this study is to evaluate the safety, tolerability, and effectiveness of study drug called CpG 1018 ISS to slow or prevent Alzheimer ...Phase
TRIAL ROLE: Principal Investigator
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A Phase 2A Randomized Double-Blind Placebo-Controlled Trial to Evaluate the Efficacy and Safety of varoglutamstat (PQ912) in Patients with Early Alzheimer s Disease with a Stage Gate to Phase 2B (VIVA-MIND)
The purpose of this study is to learn more about the safety and effectiveness of the study drug called varoglutamstat which may delay or slow ...Phase
TRIAL ROLE: Principal Investigator
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Neuroenergetic Adaptations in Alzheimer's Disease: Implications on Amyloid Burden and Cognition
The purpose of this study is to see if there is a relationship between energy production in the brain and risk for Alzheimer's disease ...Phase N/A
Accepts Healthy Volunteer
TRIAL ROLE: Sub Investigator
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Anti-viral therapy in Alzheimer's disease
This study is being conducted to evaluate if the generic anti-viral medication, valacyclovir, is helpful in treating Alzheimer's disease in patients who have tested positive ...Phase
TRIAL ROLE: Sub Investigator
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A Single-Center Observational Longitudinal Study on the Effect of Slow Wave Sleep (SWS) Characteristics and Race and Ethnicity on Amyloid Burden (A Marker of Alzheimer s Disease Risk) among cognitively normal elderly
Sleep AWARE is a research study funded by the National Institutes of Health and the National Institutes for Aging. We will examine how race, genes ...
Phase N/A Accepts Healthy Volunteer
TRIAL ROLE: Sub Investigator
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Sleep Aging and Risk for Alzheimer's
Age-related sleep changes and common sleep disorders like obstructive sleep apnea (OSA) may increase amyloid burden and represent risk factors for cognitive decline. In this ...Phase N/A Accepts Healthy Volunteer
TRIAL ROLE: Sub Investigator
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Understanding CSF Clearance in Aging and Alzheimer s Brain Through Dynamic Sodium MRI
This study aims to determine: 1) how age affects CSF production, bulk flow, and drainage in the normal brain; 2) the impact of sleep on ...Phase N/A Accepts Healthy Volunteer
TRIAL ROLE: Sub Investigator
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Racial diffErences in the aSsociation Of sLow waVe slEep aNd Tau (RESOLVENT II)
The purpose of this research study is to is to test whether poor slow wave sleep (SWS), the most restful sleep stage, is one of ...Phase N/A Accepts Healthy Volunteer
TRIAL ROLE: Sub Investigator
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Race-spEcific regional Tau deposition and role of Obstructive Sleep Apnea (RETOSA)
The purpose of this research study is to test whether racial differences exist in markers of brain loss in Alzheimer's disease and if Obstructive ...Phase N/A Accepts Healthy Volunteer
TRIAL ROLE: Sub Investigator
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Brain Fog Following COVID-19 (SARS-COV-2 Infection) <br> Healthy COVID negative volunteers needed
The purpose of this study is to examine whether or not individuals who were previously diagnosed with SARS-CoV-2, or COVID-19, have greater cognitive and biomarker ...Phase N/A Accepts Healthy Volunteer
TRIAL ROLE: Sub Investigator
