9 clinical trials found.
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A phase 3 multicenter randomized double-blind placebo-controlled active reference (adalimumab) study evaluating the efficacy and safety of bimekizumab in the treatment of subjects with active psoriatic arthritis
Psoriasis is a long-term skin disease in which the skin cells grow abnormally causing a buildup of cells which appears as red, raised patches covered ...Phase
Interventional
TRIAL ROLE: Sub Investigator
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A multicenter phase 3 randomized double-blind placebo-controlled study evaluating the efficacy and safety of bimekizumab in the treatment of subjects with active psoriatic arthritis
Psoriasis is a long-term skin disease in which the skin cells grow abnormally causing a buildup of cells which appears as red, raised patches covered ...Phase
Interventional
TRIAL ROLE: Sub Investigator
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A randomized double -blind placebo-controlled study to evaluate the efficacy and safety of sarilumab in patients with polymyalgia rheumatic
In this study, the study drug, sarilumab, is investigational and needs to be tested to know if it is safe and effective for your disease ...Phase
Interventional
TRIAL ROLE: Sub Investigator
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A randomized double-blind parallel-group multicenter study of secukinumab to compare 300 mg and 150 mg at Week 52 in patients with Ankylosing Spondylitis who are randomized to dose escalation after not achieving inactive disease during an initial 16 weeks of open-label treatment with secukinumab 150 mg (ASLeap)
The purpose of the study is to determine the safety and benefit of taking secukinumab 300mg, compared to 150mg, in patients with active ankylosing spondylitis ...Phase
Interventional
TRIAL ROLE: Sub Investigator
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A Multicentre Randomised Double-blind Placebo-Controlled Phase 3 Extension Study to Characterise the Long-term Safety and Tolerability of Anifrolumab in Adult Subjects with Active Systemic Lupus Erythematosus
Lupus is an autoimmune disease, which means that your immune system attacks the tissues and organs of your own body. Lupus can cause fever, fatigue ...Phase
Interventional
TRIAL ROLE: Sub Investigator
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A Multicenter Open-Label Extension Study to Assess the Long-Term Safety Tolerability and Efficacy of Bimekizumab in the Treatment of Subjects with Active Psoriatic Arthritis
The purpose of this study is to help us understand how safe, effective and tolerable an investigational new drug called bimekizumab (bye-me-key-zoo-mab) is for a ...Phase
Interventional
TRIAL ROLE: Sub Investigator
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A Phase 2B Double-Blind Randomized Placebo-Controlled Multicenter Dose-Ranging Study to Evaluate the Efficacy and Safety Profile of PF-06700841 in Participants with Active Systemic Lupus Erythematosus (SLE)
The purpose of this study is to compare the effects of the study drug PF 06700841 tablets, at different doses with a placebo to find ...Phase
Interventional
TRIAL ROLE: Sub Investigator
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A Phase 2 Study to Investigate the Safety and Efficacy of Elsubrutinib and Upadacitinib Given Alone or in Combination (ABBV-599 Combination) in Subjects with Moderately to Severely Active Systemic Lupus Erythematosus
The purpose of this study is to understand how safe and effective a new investigational drug elsubrutinib, upadacitinib, and elsubrutinib vs placebo for the treatment ...Phase
Interventional
TRIAL ROLE: Sub Investigator
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Efficacy and safety of GSK3196165 versus placebo and tofacitinib in participants with moderately to severely active rheumatoid arthritis who have an inadequate response to conventional synthetic/biologic DMARDs.
This study will compare otilimab with tofacitinib or placebo in addition to your current csDMARD treatment(s), which you will continue to receive. Otilimab is ...Phase
Interventional
TRIAL ROLE: Sub Investigator
