4 clinical trials found.
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A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation
The purpose of this study is to test the safety, tolerability, and effectiveness of MRTX849 (called “the study drug” from now on) for advanced cancers ... -
A Randomized Double-Blind Placebo-Controlled Phase 2 Study Comparing the Efficacy and Safety of Tirzepatide versus Placebo in Patients with Nonalcoholic Steatohepatitis (NASH)
This study will examen whether the investigational drug, tirzepatide, is safe and able to help study participants with nonalcoholic steatohepatitis (NASH). “Investigational” means that the ... -
A Phase 1 Multicenter Dose Escalation and Dose Expansion Study of Antibody-Drug Conjugate MYTX-011 in Subjects with Non-Small Cell Lung Cancer
This study is for patients with non-small cell lung cancer (NSCLC). In Part 1 of the study, we will enroll patients to test the safety ...
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KontRASt-03: A Phase Ib/II multicenter open-label platform study of JDQ443 with select combinations in patients with advanced solid tumor harboring the KRAS G12C mutation
This study will focus on two types of cancer: non-small cell lung cancer and colorectal cancer. The purpose of the study is to find out ...